If the play Twelve Angry Men was set in modern times, what are three ways that it would be different?

This question is very much an opinion based question. It is up to you to decide how this play might be changed for modern day audiences. Some of the changes could be huge, while other changes could be incredibly minor changes. Your main job is going to be to adequately justify why you think those changes would/should be made. Here are a few changes that I think might be changed for modern day audiences.
The jury wouldn't be comprised of only men. The jury would contain women as well. At one point in American history, women were not allowed to be jury members; however, that is not the case anymore. A modernized play would likely go for a balanced jury of 6 men and 6 women.
The previous change would almost assuredly mandate a title change to 12 Angry Jurors.

The jury would be comprised of only women, and the play would be called 12 Angry Women. This is not that far of a stretch. Swapping out the previous all-male foursome of the Ghostbusters crew happened in the recent remake of the film, and all four of the new Ghostbusters are female. A female cast reboot of Ocean's 11 is also currently in the works.
The murder weapon would be a gun. There is no reason that a knife wouldn't still work for modern day audiences, but with as much as gun control is in the media, it makes sense that a director or writer would want to bring gun violence into the spotlight.