What is a concise and open-ended discussion question, related to this story?

I believe that this question is asking for a single question that is both concise and open ended rather than a question that is concise and one that is open ended. I'll try to give a couple of possible questions that could be asked about this story. Some of the questions could be asked at any point while reading the novel, but other questions might be best asked at particular moments in the story.
How does Cole feel about his own ethnic diversity?
How does Cole feel about his Native American roots?
How does Cole's dream reflect his own emotional turmoil?
How does the strange apparition foreshadow Cole's eventual identity crisis?
How does Alex affect Cole's view of himself?
What are some basic themes of this story?
How is this story a good example of "magical realism" in literature?