How does anti-transcendentalism relate to "Rappaccini’s Daughter?"

Transcendentalists believed in the divinity of nature. Many, like Ralph Waldo Emerson, thought that when we are in nature, something very special happens to us. We return to a childlike state of innocence, and, at the same time, we are restored to both reason and faith. Many believed in something called the Oversoul, which was a trinity of sorts consisting of humankind, nature, and God. They thought that connecting with nature would bring us closer to God and help us to understand ourselves better.
In "Rappaccini's Daughter," however, nature is not a good and blessed thing, made by God, with the power to restore and revive us; instead, it is something corrupt and poisonous, made by man, having the power to weaken and destroy us. Hawthorne presents a very different view of what nature can be, especially when meddled with by humans. It becomes destructive and menacing.