What are some aspects of morality in Frankenstein?

The key moral quandary in Mary Shelley's Frankenstein is one that was much debated at the time of writing; that is, how far can, or should, man play God? In this novel, Shelley presents an issue that had begun to arise during the Enlightenment period; the novel is concerned with how far the advancement of science might result in people forgetting their place in the world, overreaching and attempting to set themselves up almost as gods. Frankenstein's excessive hubris leads to his downfall, after he creates another person without having the personal capacity to look after or properly govern his creation. The moral quandary here, then, is: should we put science to as many uses as we can, without consideration for whether or not these uses are moral? Is it moral to create another being, and then leave that being to survive on its own, feeling dejected because it knows it has no soul?
The concept of the soul, too, is interrogated through the creature Frankenstein makes. Frankenstein does not account for the creature's needing companionship or the fact that the being is alive and aware of its own shortcomings. Frankenstein has taken upon himself the task of creating this being to pursue his own self-interest, but he has put his own thoughts of achievement ahead of any consideration of how the creature, itself, might feel. He has not paused to consider the question of the soul, what it is, and who is responsible for it.